Blar i ODA Open Digital Archive på forfatter "Toft, Mathias"

Viser treff 1-7 av 7

    • Allele-specific expression of Parkinson’s disease susceptibility genes in human brain 

      Langmyhr, Margrete; Henriksen, Sandra Pilar; Cappelletti, Chiara; van de Berg, Wilma D. J.; Pihlstrøm, Lasse; Toft, Mathias (Scientific Reports;11, Article number: 504 (2021), Peer reviewed; Journal article, 2021-01-12)
      Genome-wide association studies have identifed genetic variation in genomic loci associated with susceptibility to Parkinson’s disease (PD), the most common neurodegenerative movement disorder worldwide. We used allelic ...

    • Impulsivity in Parkinson’s disease patients treated with subthalamic nucleus deep brain stimulation—An exploratory study 

      Pham, Uyen Ha Gia; Skogseid, Inger Marie; Pripp, Are Hugo; Bøen, Erlend; Toft, Mathias (PLOS ONE;16(3): e0248568, Peer reviewed; Journal article, 2021-03-12)
      Background: Deep brain stimulation of the subthalamic nucleus (STN-DBS) is a recognized treatment in Parkinson’s disease (PD). Knowledge is still limited regarding the possible impact of STN-DBS on personality traits and ...

    • Intelligent digital tools for screening of brain connectivity and dementia risk estimation in people affected by mild cognitive impairment: the AI-Mind clinical study protocol 

      Haraldsen, Ira Hebold; Hatlestad-Hall, Christoffer; Marra, Camillo; Renvall, Hanna; Maestú, Fernando; Acosta-Hernández, Jorge; Alfonsin, Soraya; Andersson, Vebjørn; Anand, Abhilash; Ayllón, Victor; Babic, Aleksandar; Belhadi, Asma; Birck, Cindy; Bruña, Ricardo; Caraglia, Naike; Carrarini, Claudia; Christensen, Erik; Cicchetti, Americo; Daugbjerg, Signe; Di Bidino, Rossella; Diaz-Ponce, Ana; Drews, Ainar; Giuffrè, Guido Maria; Georges, Jean; Gil-Gregorio, Pedro; Gove, Dianne; Govers, Tim M.; Hallock, Harry; Hietanen, Marja; Holmen, Lone; Hotta, Jaakko; Kaski, Samuel; Khadka, Rabindra; Kinnunen, Antti S.; Koivisto, Anne M.; Kulashekhar, Shrikanth; Larsen, Denis; Liljeström, Mia; Lind, Pedro; Marcos Dolado, Alberto; Marshall, Serena; Merz, Susanne; Miraglia, Francesca; Montonen, Juha; Mäntynen, Ville; Øksengård, Anne Rita; Olazarán, Javier; Paajanen, Teemu; Peña, José M.; Peña, Luis; Peniche, Daniel lrabien; Sanz Perez, Ana; Radwan, Mohamed; Ramírez-Toraño, Federico; Rodríguez-Pedrero, Andrea; Saarinen, Timo; Salas-Carrillo, Mario; Salmelin, Riitta; Sousa, Sonia; Suyuthi, Abdillah; Toft, Mathias; Toharia, Pablo; Tveitstøl, Thomas; Tveter, Mats; Upreti, Ramesh; Vermeulen, Robin J.; Vecchio, Fabrizio; Yazidi, Anis; Rossini, Paolo Maria (Peer reviewed; Journal article, 2023)
      More than 10 million Europeans show signs of mild cognitive impairment (MCI), a transitional stage between normal brain aging and dementia stage memory disorder. The path MCI takes can be divergent; while some maintain ...

    • Paramedic Norwegian Acute Stroke Prehospital Project (ParaNASPP) study protocol: a stepped wedge randomised trial of stroke screening using the National Institutes of Health Stroke Scale in the ambulance 

      Bugge, Helge Fagerheim; Guterud, Mona; Bache, Kristi Cecilie Grønvold; Braarud, Anne-Cathrine; Eriksen, Erik; Fremstad, Kjell Otto; Ihle-Hansen, Hege; Ingebretsen, Svein Håkon; Kramer-Johansen, Jo; Larsen, Karianne; Røislien, Jo; Thorsen, Kjetil; Toft, Mathias; Sandset, Else Charlotte; Hov, Maren Ranhoff (Trials;23, Article number: 113 (2022), Peer reviewed; Journal article, 2022-02-04)
      Background: Less than 50% of stroke patients in Norway reach hospital within 4 h of symptom onset. Early prehospital identification of stroke and triage to the right level of care may result in more patients receiving acute ...

    • Pleiotropy with sex-specific traits reveals genetic aspects of sex differences in Parkinson's disease 

      Nordengen, Kaja; Cappelletti, Chiara; Bahrami, Shahram; Frei, Oleksandr; Pihlstrøm, Lasse; Henriksen, Sandra Pilar; Geut, Hanneke; Rozemuller, Annemieke J M; Berg, Wilma D J van de; Andreassen, Ole; Toft, Mathias (Peer reviewed; Journal article, 2023)
      Parkinson’s disease is an age-related neurodegenerative disorder with a higher incidence in males than females. The causes for this sex difference are unknown. Genome-wide association studies (GWAS) have identified 90 ...

    • Prehospital screening of acute stroke with the National Institutes of Health Stroke Scale (ParaNASPP): a stepped-wedge, cluster-randomised controlled trial 

      Guterud, Mona; Bugge, Helge Fagerheim; Røislien, Jo; Kramer-Johansen, Jo; Toft, Mathias; Ihle-Hansen, Hege Beathe; Bache, Kristi Cecilie Grønvold; Larsen, Karianne; Braarud, Anne-Cathrine; Sandset, Else Charlotte; Hov, Maren Ranhoff (Peer reviewed; Journal article, 2023)
      Background Timely treatment of acute stroke depends on early identification and triage. Improved methods for recognition of stroke in the prehospital setting are needed. We aimed to assess whether use of the National ...

    • Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expression changes 

      Cappelletti, Chiara; Henriksen, Sandra Pilar; Geut, Hanneke; Rozemuller, Annemieke J. M.; van de Berg, Wilma D. J.; Pihlstrøm, Lasse; Toft, Mathias (Peer reviewed; Journal article, 2023)
      Parkinson´s disease (PD) is a progressive neurodegenerative disorder characterized by both motor and non-motor symptoms. Aggravation of symptoms is mirrored by accumulation of protein aggregates mainly composed by ...